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Presbyterian/St. Luke’s Medical Center

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Rocky Mountain Hospital For Children at P/SL

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Leslie S Gamache, MD

Leslie S Gamache, MD

Leslie Gamache, MD was born and raised in Denver, Colorado. She received a BA degree from Carleton College in Minnesota and an MD degree from Creighton University in Omaha. Dr. Gamache's passion is for clinical medicine, but she has a strong foundation in research, which began in the Department of Neurology at Northwestern University. She has several publications in the field of endocrinology and is a two-time winner of the Western American Federation of Medical Research Scholar Award. She currently sits on the Diabetes Management Advisory Board at PSL, as well as the in-patient diabetes multi-disciplinary committee. Dr. Gamache's areas of interest include thyroid disorders, diabetes, osteoporosis and disorders of the adrenal and pituitary gland. She also has an interest in hormonal and metabolic bone disorders follow cancer treatments. Outside of the office, Dr. Gamache enjoys spending time with her family, running with friends and doing crossfit bootcamp.
Care Philosophy

At Denver Endocrinology, we are a small, patient-oriented practice conveniently located in Denver between City Park and downtown. We are general endocrinologists who see a wide spectrum of endocrine disorders, including diabetes (Type 1, Type 2 and gestational), thyroid disease, thyroid cancer, osteoporosis, calcium disorders, pituitary dysfunction and a variety of other hormonal disorders. We believe in a cooperative approach to health and strive to maintain close communication with our patients and their providers.

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Blue Cross Blue Shield

Capital District Physicians' Health Plan (CDPHP)


Calcium or Bone Disorders

Cancer Involving an Endocrine Gland



Lipid Disorders

Metabolic Disorders


Overproduction or Underproduction of Hormones

Polycystic Ovarian Syndrome (PCOS)

Thyroid Disease

  • Diabetes - Board Certified
  • Endocrinology - Primary - Board Certified
  • Graduate Degree: Doctor Of Medicine - Creighton University - 2001
  • Residency: University of New Mexico - 2004
  • Fellowship: University of New Mexico - 2006
  • Internship: University of New Mexico
  • English
  • Spanish
  • Presbyterian St Lukes Medical Center
  • Swedish Medical Center